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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50087104'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neprilysin


(Oryctolagus cuniculus (rabbit))
BDBM50087104
PNG
(C-{[3-Biphenyl-4-yl-2-(carboxymethyl-carbamoyl)-pr...)
Show SMILES [NH3+][C@H](c1ccccc1)P(O)(=O)C[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)NCC(O)=O
Show InChI InChI=1S/C25H27N2O5P/c26-24(21-9-5-2-6-10-21)33(31,32)17-22(25(30)27-16-23(28)29)15-18-11-13-20(14-12-18)19-7-3-1-4-8-19/h1-14,22,24H,15-17,26H2,(H,27,30)(H,28,29)(H,31,32)/p+1/t22-,24+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
PubMed
0.940n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity on neutral endopeptidase (NEP) using DGNPA as substrate.


J Med Chem 43: 1398-408 (2001)


BindingDB Entry DOI: 10.7270/Q2TQ627J
More data for this
Ligand-Target Pair