Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neprilysin (Homo sapiens (Human)) | BDBM50105262 (2-{3-[(1-Amino-ethyl)-hydroxy-phosphinoyl]-2-biphe...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Compound was evaluated for inhibition of enkephalin degrading enzyme, neutral endopeptidase (NEP) | J Med Chem 44: 3523-30 (2001) BindingDB Entry DOI: 10.7270/Q2QN67HK | |||||||||||
More data for this Ligand-Target Pair |