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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50190767'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Homo sapiens (Human))		BDBM50190767
PNG
(2-((1-((3-(dimethylcarbamoyl)cyclohexyl)carbamoyl)...)
Show SMILES CCCC(CC1(CCCC1)C(=O)NC1CCCC(C1)C(=O)N(C)C)C(O)=O
Show InChI InChI=1S/C21H36N2O4/c1-4-8-16(19(25)26)14-21(11-5-6-12-21)20(27)22-17-10-7-9-15(13-17)18(24)23(2)3/h15-17H,4-14H2,1-3H3,(H,22,27)(H,25,26)
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KEGG

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PC cid
PC sid
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Patents

Similars
Article
PubMed
n/an/a 297n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP

J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair