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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50190777'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Homo sapiens (Human))		BDBM50190777
PNG
(2-((1-(((1R,2R)-2-benzylcyclohexyl)carbamoyl)cyclo...)
Show SMILES CCCC(CC1(CCCC1)C(=O)N[C@@H]1CCCC[C@@H]1Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C25H37NO3/c1-2-10-21(23(27)28)18-25(15-8-9-16-25)24(29)26-22-14-7-6-13-20(22)17-19-11-4-3-5-12-19/h3-5,11-12,20-22H,2,6-10,13-18H2,1H3,(H,26,29)(H,27,28)/t20-,21?,22-/m1/s1
PDB

KEGG

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 195n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP

J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair