new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50287299'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neprilysin


(Homo sapiens (Human))
BDBM50287299
PNG
((2S,4S)-5-Biphenyl-4-yl-4-(4-carboxymethyl-thiazol...)
Show SMILES OC(=O)Cc1csc(NC(=O)[C@@H](C[C@@H](COc2ccccc2)C(O)=O)Cc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C30H28N2O6S/c33-27(34)17-25-19-39-30(31-25)32-28(35)23(16-24(29(36)37)18-38-26-9-5-2-6-10-26)15-20-11-13-22(14-12-20)21-7-3-1-4-8-21/h1-14,19,23-24H,15-18H2,(H,33,34)(H,36,37)(H,31,32,35)/t23-,24+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a 0.690n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Neutral Endopeptidase


Bioorg Med Chem Lett 6: 1487-1490 (1996)


Article DOI: 10.1016/S0960-894X(96)00255-7
BindingDB Entry DOI: 10.7270/Q2B27VSQ
More data for this
Ligand-Target Pair