new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neuraminidase A (NanA)' and Ligand = 'BDBM4994'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuraminidase A (NanA)


(Streptococcus pneumoniae)
BDBM4994
PNG
((3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)c...)
Show SMILES CCC(CC)O[C@@H]1C=C(C[C@H](N)[C@H]1NC(C)=O)C(O)=O |r,c:7|
Show InChI InChI=1S/C14H24N2O4/c1-4-10(5-2)20-12-7-9(14(18)19)6-11(15)13(12)16-8(3)17/h7,10-13H,4-6,15H2,1-3H3,(H,16,17)(H,18,19)/t11-,12+,13+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents

PDB
Article
PubMed
1.77E+3n/an/an/an/an/an/a9.0n/a



UniversitÓ degli Studi di Siena



Assay Description
Briefly, the reaction mixtures containing the substrates and up to 100 nM sialidase were incubated at 37░C and stopped by the addition of 0.5 M Na2CO...


BMC Biochem 13: 19 (2012)


Article DOI: 10.1186/1471-2091-13-19
BindingDB Entry DOI: 10.7270/Q2959GDQ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)