Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neuromedin-K receptor' and Ligand = 'BDBM233265'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuromedin-K receptor (Homo sapiens (Human))	BDBM233265 (US9346786, 69) Show SMILES CCN([C@@H]1CN(C[C@H]1c1ccc(Cl)c(F)c1)C(=O)C1CCN(CC1)C(=O)C1CC(F)C1)C(=O)Oc1ccc(F)cc1 |r,wU:7.8,wD:3.2,(6.08,.05,;5.31,-1.28,;3.77,-1.28,;3,.05,;1.46,.05,;.99,1.51,;2.23,2.42,;3.48,1.51,;4.97,1.91,;6.06,.82,;7.54,1.22,;7.94,2.71,;9.43,3.11,;6.85,3.8,;7.25,5.29,;5.37,3.4,;-.5,1.91,;-.9,3.4,;-1.59,.82,;-1.19,-.66,;-2.28,-1.75,;-3.77,-1.35,;-4.16,.13,;-3.08,1.22,;-4.86,-2.44,;-4.46,-3.93,;-6.34,-2.04,;-7.11,-.71,;-8.45,-1.48,;-9.93,-1.08,;-7.68,-2.81,;3,-2.62,;1.46,-2.62,;3.77,-3.95,;5.31,-3.95,;6.08,-2.62,;7.62,-2.62,;8.39,-3.95,;9.93,-3.95,;7.62,-5.29,;6.08,-5.29,)| Show InChI InChI=1S/C30H33ClF3N3O4/c1-2-37(30(40)41-23-6-4-21(32)5-7-23)27-17-36(16-24(27)19-3-8-25(31)26(34)15-19)28(38)18-9-11-35(12-10-18)29(39)20-13-22(33)14-20/h3-8,15,18,20,22,24,27H,2,9-14,16-17H2,1H3/t20?,22?,24-,27+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2	-46.2	n/a	n/a	n/a	n/a	n/a	7.4	4
Hoffmann-La Roche Inc. US Patent					Assay Description hNK3 receptor binding experiment were performed using [3H]SR142801 (Catalog No. TRK1035, specific activity: 74.0 Ci/mmol, Amersham, GE Healthcare UK ...				US Patent US9346786 (2016) BindingDB Entry DOI: 10.7270/Q20V8BPC
					More data for this Ligand-Target Pair