Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-4' and Ligand = 'BDBM50264763'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50264763 (3-(2-chlorothiophen-3-yl)-5-(1-(piperidin-4-yl)-1H...) Show SMILES Clc1sccc1-c1cc(on1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C15H15ClN4OS/c16-15-12(3-6-22-15)13-7-14(21-19-13)10-8-18-20(9-10)11-1-4-17-5-2-11/h3,6-9,11,17H,1-2,4-5H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced current				Bioorg Med Chem Lett 18: 5209-12 (2008) Article DOI: 10.1016/j.bmcl.2008.08.080 BindingDB Entry DOI: 10.7270/Q2SX6D26
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