BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-4' and Ligand = 'BDBM50264798'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-4


(Homo sapiens (Human))
BDBM50264798
PNG
(3-(2-chlorophenyl)-5-(2-(piperidin-4-yl)thiazol-5-...)
Show SMILES Clc1ccccc1-c1cc(on1)-c1cnc(s1)C1CCNCC1
Show InChI InChI=1S/C17H16ClN3OS/c18-13-4-2-1-3-12(13)14-9-15(22-21-14)16-10-20-17(23-16)11-5-7-19-8-6-11/h1-4,9-11,19H,5-8H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 33n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced current


Bioorg Med Chem Lett 18: 5209-12 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.080
BindingDB Entry DOI: 10.7270/Q2SX6D26
More data for this
Ligand-Target Pair