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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-4' and Ligand = 'BDBM50264799'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-4


(Homo sapiens (Human))		BDBM50264799
PNG
(3-(2-chloro-6-fluorophenyl)-5-(1-methyl-2-(piperid...)
Show SMILES Cn1c(cnc1C1CCNCC1)-c1cc(no1)-c1c(F)cccc1Cl
Show InChI InChI=1S/C18H18ClFN4O/c1-24-15(10-22-18(24)11-5-7-21-8-6-11)16-9-14(23-25-16)17-12(19)3-2-4-13(17)20/h2-4,9-11,21H,5-8H2,1H3
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PC cid
PC sid
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Similars
Article
PubMed
n/an/an/an/a 12n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced current

Bioorg Med Chem Lett 18: 5209-12 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.080
BindingDB Entry DOI: 10.7270/Q2SX6D26
More data for this
Ligand-Target Pair