Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM322292'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM322292 (6-methyl-N-(1''-azaspiro[cyclopropane-1,2''-bicycl...) Show SMILES Cc1ccc2cc(sc2c1)C(=O)NC1C2CCN(CC2)C11CC1 Show InChI InChI=1S/C19H22N2OS/c1-12-2-3-14-11-16(23-15(14)10-12)18(22)20-17-13-4-8-21(9-5-13)19(17)6-7-19/h2-3,10-11,13,17H,4-9H2,1H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axovant Sciences GmbH US Patent					Assay Description The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...				US Patent US10183938 (2019) BindingDB Entry DOI: 10.7270/Q2VD71JR
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM322292 (6-methyl-N-(1''-azaspiro[cyclopropane-1,2''-bicycl...) Show SMILES Cc1ccc2cc(sc2c1)C(=O)NC1C2CCN(CC2)C11CC1 Show InChI InChI=1S/C19H22N2OS/c1-12-2-3-14-11-16(23-15(14)10-12)18(22)20-17-13-4-8-21(9-5-13)19(17)6-7-19/h2-3,10-11,13,17H,4-9H2,1H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axovant Sciences GmbH US Patent					Assay Description The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...				US Patent US10183938 (2019) BindingDB Entry DOI: 10.7270/Q2VD71JR
					More data for this Ligand-Target Pair