Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50416404'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50416404 (CHEMBL1210577) Show SMILES O=C(Cn1nc(C2CCCCC2)c2ccccc2c1=O)NC1Cc2ccccc2C1 Show InChI InChI=1S/C25H27N3O2/c29-23(26-20-14-18-10-4-5-11-19(18)15-20)16-28-25(30)22-13-7-6-12-21(22)24(27-28)17-8-2-1-3-9-17/h4-7,10-13,17,20H,1-3,8-9,14-16H2,(H,26,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.94	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human alpha7 nAChR expressed in rat GH4C1 assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 20: 4561-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.014 BindingDB Entry DOI: 10.7270/Q2959JSG
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