Search and Browse
Download
Enter Data
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Neuropeptide FF receptor 1 (Homo sapiens (Human)) | BDBM50336912 (Adamantane-1-carboxylic acid [(S)-1-((S)-1-carbamo...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting method | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00256 BindingDB Entry DOI: 10.7270/Q2VX0MDH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Neuropeptide FF receptor 1 (Homo sapiens (Human)) | BDBM50336912 (Adamantane-1-carboxylic acid [(S)-1-((S)-1-carbamo...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Strasbourg Curated by ChEMBL | Assay Description Displacement of [3H]FFRF-NH2 from human flag-tagged NPFF1 receptor expressed in CHO cells by scintillation counting | Bioorg Med Chem Lett 22: 7471-4 (2012) Article DOI: 10.1016/j.bmcl.2012.10.049 BindingDB Entry DOI: 10.7270/Q2FF3THX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Neuropeptide FF receptor 1 (Homo sapiens (Human)) | BDBM50336912 (Adamantane-1-carboxylic acid [(S)-1-((S)-1-carbamo...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I]YVP from human NPFFR1 expressed in CHO cells | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00643 BindingDB Entry DOI: 10.7270/Q2SJ1QC8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Neuropeptide FF receptor 1 (Homo sapiens (Human)) | BDBM50336912 (Adamantane-1-carboxylic acid [(S)-1-((S)-1-carbamo...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
Lanzhou University Curated by ChEMBL | Assay Description Antagonist activity at NPFF1 receptor (unknown origin) expressed in HEK293A cells assessed as reversal of NPPF induced inhibition of forskolin-stimul... | Bioorg Med Chem 27: 630-643 (2019) Article DOI: 10.1016/j.bmc.2019.01.003 BindingDB Entry DOI: 10.7270/Q2M61PJ3 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Neuropeptide FF receptor 1 (Homo sapiens (Human)) | BDBM50336912 (Adamantane-1-carboxylic acid [(S)-1-((S)-1-carbamo...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.70E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at human NPFFR1 expressed in CHO cells assessed as reversal of NPVF-induced inhibition of forskolin-stimulated cAMP accumulation ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00643 BindingDB Entry DOI: 10.7270/Q2SJ1QC8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Neuropeptide FF receptor 1 (Homo sapiens (Human)) | BDBM50336912 (Adamantane-1-carboxylic acid [(S)-1-((S)-1-carbamo...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 71 | n/a | n/a | n/a | n/a |
Leipzig University Curated by ChEMBL | Assay Description Agonist activity at human NPFF1 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ... | J Med Chem 55: 6124-36 (2012) Article DOI: 10.1021/jm300535s BindingDB Entry DOI: 10.7270/Q26974PV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
