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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neuropeptide Y receptor type 1' and Ligand = 'BDBM50078996'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuropeptide Y receptor type 1


(Homo sapiens (Human))
BDBM50078996
PNG
(1-(3,5-Difluoro-phenyl)-3-{1-[3-(3-isopropyl-ureid...)
Show SMILES CC(C)NC(=O)Nc1cccc(CN2c3ccccc3CCC(NC(=O)Nc3cc(F)cc(F)c3)C2=O)c1
Show InChI InChI=1S/C28H29F2N5O3/c1-17(2)31-27(37)32-22-8-5-6-18(12-22)16-35-25-9-4-3-7-19(25)10-11-24(26(35)36)34-28(38)33-23-14-20(29)13-21(30)15-23/h3-9,12-15,17,24H,10-11,16H2,1-2H3,(H2,31,32,37)(H2,33,34,38)
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PC cid
PC sid
UniChem
Article
PubMed
86n/an/an/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Neuropeptide Y receptor type 1 was determined as potency to displace [125I]-peptide YY binding to human neuroblasto...


J Med Chem 42: 2621-32 (1999)


Article DOI: 10.1021/jm990044m
BindingDB Entry DOI: 10.7270/Q2XK8DRQ
More data for this
Ligand-Target Pair