Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neutral ceramidase (Homo sapiens (Human)) | BDBM50392472 (CHEMBL408217) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Humboldt Universit£t zu Berlin Curated by ChEMBL | Assay Description Inhibition of recombinant human nCDase expressed in Sf9 cells using fluorescently-labeled acyl-NBD-C12-ceramide as substrate after 2 hrs by fluoresce... | Bioorg Med Chem 20: 6162-70 (2012) Article DOI: 10.1016/j.bmc.2012.08.031 BindingDB Entry DOI: 10.7270/Q29Z960Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutral ceramidase (Homo sapiens (Human)) | BDBM50392472 (CHEMBL408217) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Humboldt Universit£t zu Berlin Curated by ChEMBL | Assay Description Inhibition of human recombinant neutral ceramidase using Acyl-NBD-C12-cer as substrate after 2 hrs by fluorescence assay | Bioorg Med Chem 21: 874-82 (2013) Article DOI: 10.1016/j.bmc.2012.12.014 BindingDB Entry DOI: 10.7270/Q29Z9673 | |||||||||||
More data for this Ligand-Target Pair |