Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nicotinamide phosphoribosyltransferase' and Ligand = 'BDBM186994'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM186994 (US9169209, Table 3, Compound 25) Show SMILES CC(C)Oc1cccc(c1)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C23H22N2O4S/c1-17(2)29-20-6-3-7-22(15-20)30(27,28)21-11-9-19(10-12-21)25-23(26)13-8-18-5-4-14-24-16-18/h3-17H,1-2H3,(H,25,26)/b13-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
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