Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM50444655 (CHEMBL3098518) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Forma Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of Nampt (unknown origin) using nicotinamide as substrate preincubated for 15 mins measured after 30 mins by mass spectrometry analysis | Bioorg Med Chem Lett 24: 337-43 (2013) Article DOI: 10.1016/j.bmcl.2013.11.006 BindingDB Entry DOI: 10.7270/Q2CJ8FZH | |||||||||||
More data for this Ligand-Target Pair |