Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nitric oxide synthase, inducible (Homo sapiens (Human)) | BDBM14320 (1-amino-isoquinoline | CHEMBL62083 | Fragment 17 |...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Rahway Curated by ChEMBL | Assay Description Inhibitory activity against inducible nitric oxide synthase (iNOS) | Bioorg Med Chem Lett 10: 1975-8 (2001) BindingDB Entry DOI: 10.7270/Q2319V30 | |||||||||||
More data for this Ligand-Target Pair |