BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Nitric oxide synthase, inducible' and Ligand = 'BDBM50209245'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50209245 (CHEMBL247378) Show SMILES [O-][N+](=O)c1cccc2cn[nH]c12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
UNED Curated by ChEMBL					Assay Description Inhibition of NOS2				Bioorg Med Chem 17: 6180-7 (2009) Article DOI: 10.1016/j.bmc.2009.07.067 BindingDB Entry DOI: 10.7270/Q2ZG6SBD
UNED Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50209245 (CHEMBL247378) Show SMILES [O-][N+](=O)c1cccc2cn[nH]c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB Article	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested to inhibit the conversion of [3H]-L-arginine to [3H]-L-citrulline catalyzed by inducible NOS from mouse macrophage J774 cells				Bioorg Med Chem Lett 5: 1573-1576 (1995) Article DOI: 10.1016/0960-894X(95)00273-V BindingDB Entry DOI: 10.7270/Q25T3KD0
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50209245 (CHEMBL247378) Show SMILES [O-][N+](=O)c1cccc2cn[nH]c12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB Article	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested to inhibit the conversion of [3H]-L-arginine to [3H]-L-citrulline catalyzed by inducible NOS from human DLD-1 cells.				Bioorg Med Chem Lett 5: 1573-1576 (1995) Article DOI: 10.1016/0960-894X(95)00273-V BindingDB Entry DOI: 10.7270/Q25T3KD0
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50209245 (CHEMBL247378) Show SMILES [O-][N+](=O)c1cccc2cn[nH]c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Christian-Albrechts-University of Kiel Curated by ChEMBL					Assay Description Inhibition of mouse recombinant iNOS expressed in Escherichia coli assessed as conversion of [gamma-14C]L-arginine to [14C]L-citrulline by radioactiv...				Eur J Med Chem 44: 2877-87 (2009) Article DOI: 10.1016/j.ejmech.2008.12.007 BindingDB Entry DOI: 10.7270/Q2KD1ZV6
Christian-Albrechts-University of Kiel Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50209245 (CHEMBL247378) Show SMILES [O-][N+](=O)c1cccc2cn[nH]c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université de Versailles Curated by ChEMBL					Assay Description Inhibition of mouse recombinant iNOS				Bioorg Med Chem 16: 5962-73 (2008) Article DOI: 10.1016/j.bmc.2008.04.056 BindingDB Entry DOI: 10.7270/Q2GB23VM
Université de Versailles Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)