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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nociceptin/mu opioid receptor' and Ligand = 'BDBM50399642'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50399642
PNG
(CHEMBL2181200)
Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O |r|
Show InChI InChI=1S/C32H48N8O6/c1-19-15-22(41)16-20(2)23(19)18-24(34)29(43)39-26(12-8-14-37-32(36)46)30(44)40-27(17-21-9-4-3-5-10-21)31(45)38-25(28(35)42)11-6-7-13-33/h3-5,9-10,15-16,24-27,41H,6-8,11-14,17-18,33-34H2,1-2H3,(H2,35,42)(H,38,45)(H,39,43)(H,40,44)(H3,36,37,46)/t24-,25-,26+,27-/m0/s1
PDB

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PC cid
PC sid
UniChem
Article
PubMed
0.570n/an/an/an/an/an/an/an/a



Vrije Universiteit Brussel

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes after 2 hrs


J Med Chem 55: 9549-61 (2012)


Article DOI: 10.1021/jm3008079
BindingDB Entry DOI: 10.7270/Q2TM7C82
More data for this
Ligand-Target Pair