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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nociceptin receptor' and Ligand = 'BDBM50015000'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nociceptin receptor


(Homo sapiens (Human))		BDBM50015000
PNG
(CHEMBL3262377)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]51CC[C@@]2(OC)[C@]([H])(C1)[C@@](C)(O)c1ccncc1)ccc3O |r,THB:10:9:17:4.5.6|
Show InChI InChI=1S/C30H36N2O4/c1-27(34,20-7-12-31-13-8-20)22-16-28-9-10-30(22,35-2)26-29(28)11-14-32(17-18-3-4-18)23(28)15-19-5-6-21(33)25(36-26)24(19)29/h5-8,12-13,18,22-23,26,33-34H,3-4,9-11,14-17H2,1-2H3/t22-,23-,26-,27+,28-,29+,30-/m1/s1
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Similars
Article
PubMed
 4.63E+3n/an/an/an/an/an/an/an/a



University of Bath

Curated by ChEMBL


Assay Description
Displacement of [3H]-N/OFQ from recombinant nociceptin opioid receptor (unknown origin) expressed in HEK cells

J Med Chem 57: 4049-57 (2014)


Article DOI: 10.1021/jm401964y
BindingDB Entry DOI: 10.7270/Q2NG4S62
More data for this
Ligand-Target Pair