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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nociceptin receptor' and Ligand = 'BDBM50259549'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nociceptin receptor


(Homo sapiens (Human))
BDBM50259549
PNG
(CHEMBL3084555 | endo-2-(8-(bis(2-chlorophenyl)meth...)
Show SMILES [H][C@]12CC[C@]([H])(C[C@](CC(N)=O)(Cc3ccc(F)cc3)C1)N2C(c1ccccc1Cl)c1ccccc1Cl |r,TLB:8:7:21:3.2|
Show InChI InChI=1S/C29H29Cl2FN2O/c30-25-7-3-1-5-23(25)28(24-6-2-4-8-26(24)31)34-21-13-14-22(34)17-29(16-21,18-27(33)35)15-19-9-11-20(32)12-10-19/h1-12,21-22,28H,13-18H2,(H2,33,35)/t21-,22-/m1/s1
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3n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Displacement of [125I][Tyr14]nociceptin from human cloned ORL1 receptor expressed in CHO cells


Bioorg Med Chem Lett 19: 2482-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.057
BindingDB Entry DOI: 10.7270/Q2D21XH9
More data for this
Ligand-Target Pair