Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2' and Ligand = 'BDBM332936'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM332936 (US10196390, Compound I-225) Show SMILES CN1CCN[C@](C)(C1=O)c1ccc(Nc2cc(nc3CNC(=O)c23)-c2c(F)cccc2F)nc1 |r| Show InChI InChI=1S/C24H22F2N6O2/c1-24(23(34)32(2)9-8-29-24)13-6-7-19(27-11-13)31-17-10-16(20-14(25)4-3-5-15(20)26)30-18-12-28-22(33)21(17)18/h3-7,10-11,29H,8-9,12H2,1-2H3,(H,28,33)(H,27,30,31)/t24-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent					Assay Description The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...				US Patent US10196390 (2019) BindingDB Entry DOI: 10.7270/Q22809Q4
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