Found 4 hits Enz. Inhib. hit(s) with Target = 'Norepinephrine transporter' and Ligand = 'BDBM50010859' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Norepinephrine transporter
(RAT) | BDBM50010859
(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)Show InChI InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3 | UniProtKB/TrEMBL
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CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
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Similars
| PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 283: 1305-22 (1997)
BindingDB Entry DOI: 10.7270/Q25Q4TMX |
More data for this Ligand-Target Pair | |
Norepinephrine transporter
(RAT) | BDBM50010859
(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)Show InChI InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3 | UniProtKB/TrEMBL
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CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
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| Article PubMed
| 33.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organon International
Curated by PDSP Ki Database
| |
Neuropharmacology 27: 399-408 (1988)
Article DOI: 10.1016/0028-3908(88)90149-9 BindingDB Entry DOI: 10.7270/Q2B27SSW |
More data for this Ligand-Target Pair | |
Norepinephrine transporter
(RAT) | BDBM50010859
(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)Show InChI InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3 | UniProtKB/TrEMBL
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CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
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| PubMed
| 66 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.,
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 226: 686-700 (1983)
BindingDB Entry DOI: 10.7270/Q2XP73D5 |
More data for this Ligand-Target Pair | |
Norepinephrine transporter
(RAT) | BDBM50010859
(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)Show InChI InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3 | UniProtKB/TrEMBL
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CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
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| PubMed
| 82.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 290: 761-7 (1999)
BindingDB Entry DOI: 10.7270/Q2HH6HNF |
More data for this Ligand-Target Pair | |