Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM285779'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285779 (US10080744, Example 4/2) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CC(F)(F)C2)-c2nnc(CC(C)(C)C(O)=O)o2)c2ccccc12)C(F)(F)F |r| Show InChI InChI=1S/C29H29F5N4O5S2/c1-4-21(29(32,33)34)38-45(41,42)20-10-9-18(16-7-5-6-8-17(16)20)23-19(11-15-12-28(30,31)13-15)35-25(44-23)24-37-36-22(43-24)14-27(2,3)26(39)40/h5-10,15,21,38H,4,11-14H2,1-3H3,(H,39,40)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285779 (US10080744, Example 4/2) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CC(F)(F)C2)-c2nnc(CC(C)(C)C(O)=O)o2)c2ccccc12)C(F)(F)F |r| Show InChI InChI=1S/C29H29F5N4O5S2/c1-4-21(29(32,33)34)38-45(41,42)20-10-9-18(16-7-5-6-8-17(16)20)23-19(11-15-12-28(30,31)13-15)35-25(44-23)24-37-36-22(43-24)14-27(2,3)26(39)40/h5-10,15,21,38H,4,11-14H2,1-3H3,(H,39,40)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.0400	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description For the RORγt construct used in the ThermoFluor assay, numbering for the nucleotide sequences was based on the reference sequence for human ROR&...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair