Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM285798'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285798 (US10080744, Example 11/9) Show SMILES C[C@H](NC(=O)c1cc(cc(c1)C1(C)CC1)-c1sc(nc1CC1CCCCC1)-c1noc(CC(C)(C)OC=O)n1)C(F)(F)F |r| Show InChI InChI=1S/C31H37F3N4O4S/c1-18(31(32,33)34)35-27(40)21-13-20(14-22(15-21)30(4)10-11-30)25-23(12-19-8-6-5-7-9-19)36-28(43-25)26-37-24(42-38-26)16-29(2,3)41-17-39/h13-15,17-19H,5-12,16H2,1-4H3,(H,35,40)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285798 (US10080744, Example 11/9) Show SMILES C[C@H](NC(=O)c1cc(cc(c1)C1(C)CC1)-c1sc(nc1CC1CCCCC1)-c1noc(CC(C)(C)OC=O)n1)C(F)(F)F |r| Show InChI InChI=1S/C31H37F3N4O4S/c1-18(31(32,33)34)35-27(40)21-13-20(14-22(15-21)30(4)10-11-30)25-23(12-19-8-6-5-7-9-19)36-28(43-25)26-37-24(42-38-26)16-29(2,3)41-17-39/h13-15,17-19H,5-12,16H2,1-4H3,(H,35,40)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description For the RORγt construct used in the ThermoFluor assay, numbering for the nucleotide sequences was based on the reference sequence for human ROR&...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair