BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM329646'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM329646
PNG
((R)-2-((S)-7-ethyl-6-((trans-4-(trifluoromethyl)cy...)
Show SMILES CC[C@@H]1N(C[C@H]2CC[C@@H](CC2)C(F)(F)F)Cc2cc(cnc12)C(=O)N[C@@H](COC(N)=O)c1ccc(cc1)S(=O)(=O)CC |r,wU:25.27,8.11,wD:2.1,5.4,(-1.61,-24.6,;-.1,-24.28,;.38,-22.82,;-.53,-21.57,;-2.07,-21.57,;-2.84,-20.24,;-2.07,-18.91,;-2.84,-17.57,;-4.38,-17.57,;-5.15,-18.91,;-4.38,-20.24,;-5.15,-16.24,;-4.38,-14.9,;-6.69,-16.24,;-5.92,-14.9,;.38,-20.33,;1.84,-20.8,;3.17,-20.03,;4.51,-20.8,;4.51,-22.34,;3.17,-23.11,;1.84,-22.34,;5.84,-20.03,;5.84,-18.49,;7.18,-20.8,;8.51,-20.03,;8.51,-18.49,;9.84,-17.72,;9.84,-16.07,;11.27,-15.25,;8.41,-15.25,;9.84,-20.8,;9.84,-22.34,;11.18,-23.11,;12.51,-22.34,;12.51,-20.8,;11.18,-20.03,;13.84,-23.11,;13.02,-24.54,;14.67,-24.54,;15.27,-22.29,;16.7,-23.11,)|
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
<100n/an/an/an/an/an/an/an/a



Vitae Pharmaceuticals, Inc.

US Patent




US Patent US9663515 (2017)


Article DOI: 10.1021/jm0500875
More data for this
Ligand-Target Pair