Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM351628'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM351628 (US9796710, Compound 11) Show SMILES CC[C@@H]1N(C[C@@H]2CC[C@H](OC2)C(F)(F)F)Cc2cc(cnc12)C(=O)N[C@@H](CO)c1ccc(cc1)S(=O)(=O)CC |r| Show InChI InChI=1S/C27H34F3N3O5S/c1-3-23-25-20(14-33(23)13-17-5-10-24(38-16-17)27(28,29)30)11-19(12-31-25)26(35)32-22(15-34)18-6-8-21(9-7-18)39(36,37)4-2/h6-9,11-12,17,22-24,34H,3-5,10,13-16H2,1-2H3,(H,32,35)/t17-,22-,23-,24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals, Inc. US Patent					Assay Description Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...				US Patent US9796710 (2017) BindingDB Entry DOI: 10.7270/Q2RN3B08
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