Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM50161154'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50161154 (CHEMBL3793036) Show SMILES Cn1ccc2c(cccc12)S(=O)(=O)N(CC(F)(F)F)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H19ClN2OS/c1-23-9-8-12-10-14(21)18-19(25-20(24)22-18)16(12)17-13-5-3-2-4-11(13)6-7-15(17)23/h2-5,10,15,17H,6-9H2,1H3,(H,22,24)/t15-,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Curated by ChEMBL					Assay Description Inverse agonist activity at recombinant human GST-tagged ROR-gamma receptor ligand binding domain assessed as inhibition of receptor and co-activator...				Bioorg Med Chem Lett 26: 2459-63 (2016) Article DOI: 10.1016/j.bmcl.2016.03.109 BindingDB Entry DOI: 10.7270/Q2QC05DC
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