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Found 1 hit Enz. Inhib. hit(s) with Target = 'O-acetylserine sulfhydrylase' and Ligand = 'BDBM50439143'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
O-acetylserine sulfhydrylase


(Mycobacterium tuberculosis)		BDBM50439143
PNG
(CHEMBL2418504)
Show SMILES COc1ccc(\C=C2/S\C(=N/c3cccc(c3)C(O)=O)N(C)C2=O)cc1OC
Show InChI InChI=1S/C20H18N2O5S/c1-22-18(23)17(10-12-7-8-15(26-2)16(9-12)27-3)28-20(22)21-14-6-4-5-13(11-14)19(24)25/h4-11H,1-3H3,(H,24,25)/b17-10-,21-20-
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Article
PubMed
n/an/a 54n/an/an/an/an/an/a



Karolinska Institutet

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis N-terminal His-6-tagged recombinant CysK1 expressed in Escherichia coli BL21 (DE3) after 20 mins by spectrop...

J Med Chem 56: 6457-66 (2013)


Article DOI: 10.1021/jm400710k
BindingDB Entry DOI: 10.7270/Q2GB25GH
More data for this
Ligand-Target Pair