Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Opioid growth factor receptor-like protein 1 (Homo sapiens (Human)) | BDBM97711 (US8476271, 17 | US8846929, 360 | US8846929, 361 | ...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent | Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin... | US Patent US8846929 (2014) BindingDB Entry DOI: 10.7270/Q2G44P04 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Opioid growth factor receptor-like protein 1 (Homo sapiens (Human)) | BDBM97711 (US8476271, 17 | US8846929, 360 | US8846929, 361 | ...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 5.70 | -43.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent | Assay Description ORL-1 Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Recepto... | US Patent US9145408 (2015) BindingDB Entry DOI: 10.7270/Q2DJ5DD3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Opioid growth factor receptor-like protein 1 (Homo sapiens (Human)) | BDBM97711 (US8476271, 17 | US8846929, 360 | US8846929, 361 | ...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 203 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent | Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin... | US Patent US8846929 (2014) BindingDB Entry DOI: 10.7270/Q2G44P04 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Opioid growth factor receptor-like protein 1 (Homo sapiens (Human)) | BDBM97711 (US8476271, 17 | US8846929, 360 | US8846929, 361 | ...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 57.2 | n/a | n/a | 7.4 | 4 |
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent | Assay Description ORL-1 Receptor [35S]GTPγS Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like (ORL-1) (... | US Patent US9145408 (2015) BindingDB Entry DOI: 10.7270/Q2DJ5DD3 | |||||||||||
More data for this Ligand-Target Pair |