Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM50252445 (CHEMBL4070855) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan plc, 2525 Dupont Drive, Irvine, CA 92612, USA. Electronic address: yajun.zheng@allergan.com. Curated by ChEMBL | Assay Description Displacement of (2S)-N-(2-pyrrol-1-ylphenyl)-1-[2-[1-(tritritiomethyl)benzimidazol-2-yl]sulfanylacetyl]pyrrolidine-2-carboxamide from recombinant hum... | Bioorg Med Chem Lett 27: 2825-2837 (2017) Article DOI: 10.1016/j.bmcl.2017.04.079 BindingDB Entry DOI: 10.7270/Q2TF00SV | |||||||||||
More data for this Ligand-Target Pair |