BindingDB PrimarySearch

Found 14 hits Enz. Inhib. hit(s) with Target = 'Oxytocin receptor' and Ligand = 'BDBM50029649'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Oxytocin receptor (Homo sapiens (Human))	BDBM50029649 (1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DrugMolDesign Curated by ChEMBL					Assay Description Displacement of [3H]-oxytocin from oxytocin receptor in human uterus tissue				J Med Chem 53: 6525-38 (2010) Article DOI: 10.1021/jm901812z BindingDB Entry DOI: 10.7270/Q20R9PMZ
DrugMolDesign Curated by ChEMBL					More data for this Ligand-Target Pair
Oxytocin receptor (Homo sapiens (Human))	BDBM50029649 (1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity was evaluated by measuring the displacement of [3H]-OT (oxytocin) from specific binding sites in uterine tissue obtained from human				J Med Chem 38: 4634-6 (1995) BindingDB Entry DOI: 10.7270/Q2ZW1JXC
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Oxytocin receptor (Homo sapiens (Human))	BDBM50029649 (1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for cloned human oxytocin receptor (OT-R)				J Med Chem 41: 2146-63 (1998) Article DOI: 10.1021/jm9800797 BindingDB Entry DOI: 10.7270/Q2SN083Z
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Oxytocin receptor (Homo sapiens (Human))	BDBM50029649 (1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of 3[H]oxytocin from human oxytocin receptor				Bioorg Med Chem Lett 12: 1405-11 (2002) BindingDB Entry DOI: 10.7270/Q2C24VRF
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Oxytocin receptor (Homo sapiens (Human))	BDBM50029649 (1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against cloned human oxytocin receptor from human embryonic kidney cells				Bioorg Med Chem Lett 8: 3081-6 (1999) Article DOI: 10.1016/S0960-894X(98)00568-X BindingDB Entry DOI: 10.7270/Q298865X
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Oxytocin receptor (Homo sapiens (Human))	BDBM50029649 (1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for human oxytocin receptor				Bioorg Med Chem Lett 9: 1311-6 (1999) BindingDB Entry DOI: 10.7270/Q23N22K9
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Oxytocin receptor (Homo sapiens (Human))	BDBM50029649 (1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Ability to displace [3H]oxytocin from human OT receptor (hOT)				Bioorg Med Chem Lett 12: 1399-404 (2002) BindingDB Entry DOI: 10.7270/Q2HT2RH4
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Oxytocin receptor (RAT)	BDBM50029649 (1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against oxytocin receptor (rOTr) in DES pretreated rat uterine				Bioorg Med Chem Lett 8: 3081-6 (1999) Article DOI: 10.1016/S0960-894X(98)00568-X BindingDB Entry DOI: 10.7270/Q298865X
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Oxytocin receptor (RAT)	BDBM50029649 (1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity was evaluated by measuring the displacement of [3H]-OT (oxytocin) from specific binding sites in uterine tissue obtained from rats				J Med Chem 38: 4634-6 (1995) BindingDB Entry DOI: 10.7270/Q2ZW1JXC
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Oxytocin receptor (RAT)	BDBM50029649 (1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for rat uterine oxytocin receptor (rOTr)				Bioorg Med Chem Lett 9: 1311-6 (1999) BindingDB Entry DOI: 10.7270/Q23N22K9
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Oxytocin receptor (RAT)	BDBM50029649 (1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DrugMolDesign Curated by ChEMBL					Assay Description Displacement of [3H]-oxytocin from oxytocin receptor in rat uterus tissue				J Med Chem 53: 6525-38 (2010) Article DOI: 10.1021/jm901812z BindingDB Entry DOI: 10.7270/Q20R9PMZ
DrugMolDesign Curated by ChEMBL					More data for this Ligand-Target Pair
Oxytocin receptor (Homo sapiens (Human))	BDBM50029649 (1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human cloned oxytocin receptor by cell based beta lactamase reporter assay				Bioorg Med Chem Lett 18: 4278-81 (2008) Article DOI: 10.1016/j.bmcl.2008.06.098 BindingDB Entry DOI: 10.7270/Q28W3D4Z
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Oxytocin receptor (RAT)	BDBM50029649 (1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Compound was tested for displacement of 3[H] oxytocin from rat OT receptor (in vitro)				Bioorg Med Chem Lett 12: 1405-11 (2002) BindingDB Entry DOI: 10.7270/Q2C24VRF
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Oxytocin receptor (Homo sapiens (Human))	BDBM50029649 (1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.60	n/a	n/a	n/a	n/a
UMR 7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Activity at human oxytocin receptor expressed in CHO cells by NFAT-luciferase gene reporter assay				J Med Chem 53: 1546-62 (2010) Article DOI: 10.1021/jm901084f BindingDB Entry DOI: 10.7270/Q2FX7BD4
UMR 7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					More data for this Ligand-Target Pair