Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Oxytocin receptor (RAT) | BDBM50326719 ((S)-2-amino-N-((1S,2S,4R)-7,7-dimethyl-1-((4-o-tol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
DrugMolDesign Curated by ChEMBL | Assay Description Displacement of [3H]-oxytocin from oxytocin receptor in rat uterus tissue | J Med Chem 53: 6525-38 (2010) Article DOI: 10.1021/jm901812z BindingDB Entry DOI: 10.7270/Q20R9PMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxytocin receptor (Homo sapiens (Human)) | BDBM50326719 ((S)-2-amino-N-((1S,2S,4R)-7,7-dimethyl-1-((4-o-tol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Antagonist activity at human cloned oxytocin receptor by cell based beta lactamase reporter assay | Bioorg Med Chem Lett 18: 4278-81 (2008) Article DOI: 10.1016/j.bmcl.2008.06.098 BindingDB Entry DOI: 10.7270/Q28W3D4Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxytocin receptor (Homo sapiens (Human)) | BDBM50326719 ((S)-2-amino-N-((1S,2S,4R)-7,7-dimethyl-1-((4-o-tol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
DrugMolDesign Curated by ChEMBL | Assay Description Displacement of [3H]-oxytocin from oxytocin receptor in human uterus tissue | J Med Chem 53: 6525-38 (2010) Article DOI: 10.1021/jm901812z BindingDB Entry DOI: 10.7270/Q20R9PMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxytocin receptor (Homo sapiens (Human)) | BDBM50326719 ((S)-2-amino-N-((1S,2S,4R)-7,7-dimethyl-1-((4-o-tol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yerkes National Primate Research Center Curated by ChEMBL | Assay Description Binding affinity to human OT receptor | Bioorg Med Chem Lett 23: 902-6 (2013) Article DOI: 10.1016/j.bmcl.2012.10.116 BindingDB Entry DOI: 10.7270/Q29Z9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxytocin receptor (RAT) | BDBM50326719 ((S)-2-amino-N-((1S,2S,4R)-7,7-dimethyl-1-((4-o-tol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Yerkes National Primate Research Center Curated by ChEMBL | Assay Description Inhibition of rat uterus OT receptor | Bioorg Med Chem Lett 23: 902-6 (2013) Article DOI: 10.1016/j.bmcl.2012.10.116 BindingDB Entry DOI: 10.7270/Q29Z9690 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxytocin receptor (RAT) | BDBM50326719 ((S)-2-amino-N-((1S,2S,4R)-7,7-dimethyl-1-((4-o-tol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-OT from binding to oxytocin receptor of rat uterus | J Med Chem 37: 565-71 (1994) BindingDB Entry DOI: 10.7270/Q21C1VZ0 | |||||||||||
More data for this Ligand-Target Pair |