Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM50415883'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415883 (CHEMBL1095454) Show SMILES Cc1nn(c(C)c1CC(=O)NCc1ccc(F)cc1Cl)-c1ccccc1 Show InChI InChI=1S/C20H19ClFN3O/c1-13-18(14(2)25(24-13)17-6-4-3-5-7-17)11-20(26)23-12-15-8-9-16(22)10-19(15)21/h3-10H,11-12H2,1-2H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39.8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay				Bioorg Med Chem Lett 20: 5080-4 (2010) Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415883 (CHEMBL1095454) Show SMILES Cc1nn(c(C)c1CC(=O)NCc1ccc(F)cc1Cl)-c1ccccc1 Show InChI InChI=1S/C20H19ClFN3O/c1-13-18(14(2)25(24-13)17-6-4-3-5-7-17)11-20(26)23-12-15-8-9-16(22)10-19(15)21/h3-10H,11-12H2,1-2H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39.8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM50415883 (CHEMBL1095454) Show SMILES Cc1nn(c(C)c1CC(=O)NCc1ccc(F)cc1Cl)-c1ccccc1 Show InChI InChI=1S/C20H19ClFN3O/c1-13-18(14(2)25(24-13)17-6-4-3-5-7-17)11-20(26)23-12-15-8-9-16(22)10-19(15)21/h3-10H,11-12H2,1-2H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of rat P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM50415883 (CHEMBL1095454) Show SMILES Cc1nn(c(C)c1CC(=O)NCc1ccc(F)cc1Cl)-c1ccccc1 Show InChI InChI=1S/C20H19ClFN3O/c1-13-18(14(2)25(24-13)17-6-4-3-5-7-17)11-20(26)23-12-15-8-9-16(22)10-19(15)21/h3-10H,11-12H2,1-2H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of rat P2X7 receptor by ethidium bromide release assay				Bioorg Med Chem Lett 20: 5080-4 (2010) Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T
					More data for this Ligand-Target Pair