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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Pancreatic lipase' and Ligand = 'BDBM50381858'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Pancreatic lipase


(Sus scrofa (Pig))
BDBM50381858
PNG
(CHEMBL2022679)
Show SMILES CCCCOc1ccc(NC(=O)CCC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(N)=O)cc1 |r|
Show InChI InChI=1S/C32H38N4O6/c1-2-3-19-42-26-15-11-24(12-16-26)34-29(38)17-18-30(39)35-28(21-22-7-5-4-6-8-22)32(41)36-27(31(33)40)20-23-9-13-25(37)14-10-23/h4-16,27-28,37H,2-3,17-21H2,1H3,(H2,33,40)(H,34,38)(H,35,39)(H,36,41)/t27-,28-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.60E+5n/an/an/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibition of porcine pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysis


Bioorg Med Chem Lett 22: 3147-51 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.048
BindingDB Entry DOI: 10.7270/Q22R3SPF
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens (Human))
BDBM50381858
PNG
(CHEMBL2022679)
Show SMILES CCCCOc1ccc(NC(=O)CCC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(N)=O)cc1 |r|
Show InChI InChI=1S/C32H38N4O6/c1-2-3-19-42-26-15-11-24(12-16-26)34-29(38)17-18-30(39)35-28(21-22-7-5-4-6-8-22)32(41)36-27(31(33)40)20-23-9-13-25(37)14-10-23/h4-16,27-28,37H,2-3,17-21H2,1H3,(H2,33,40)(H,34,38)(H,35,39)(H,36,41)/t27-,28-/m0/s1
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
5.50E+5n/an/an/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibition of human pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysis


Bioorg Med Chem Lett 22: 3147-51 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.048
BindingDB Entry DOI: 10.7270/Q22R3SPF
More data for this
Ligand-Target Pair