Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Peptidyl-glycine alpha-amidating monooxygenase' and Ligand = 'BDBM50401750'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peptidyl-glycine alpha-amidating monooxygenase (Homo sapiens (Human))	BDBM50401750 (CHEMBL2207129) Show SMILES CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)OCC(O)=O |r| Show InChI InChI=1S/C24H33N3O7/c1-15(2)12-18(25-23(32)20-10-7-11-27(20)16(3)28)22(31)26-19(24(33)34-14-21(29)30)13-17-8-5-4-6-9-17/h4-6,8-9,15,18-20H,7,10-14H2,1-3H3,(H,25,32)(H,26,31)(H,29,30)/t18-,19-,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Australian National University Curated by ChEMBL					Assay Description Competitive inhibition of PAM in human DMS53 cells using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysis				Bioorg Med Chem Lett 22: 7015-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.004 BindingDB Entry DOI: 10.7270/Q2VT1T73
					More data for this Ligand-Target Pair
Peptidyl-glycine alpha-amidating monooxygenase (Homo sapiens (Human))	BDBM50401750 (CHEMBL2207129) Show SMILES CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)OCC(O)=O |r| Show InChI InChI=1S/C24H33N3O7/c1-15(2)12-18(25-23(32)20-10-7-11-27(20)16(3)28)22(31)26-19(24(33)34-14-21(29)30)13-17-8-5-4-6-9-17/h4-6,8-9,15,18-20H,7,10-14H2,1-3H3,(H,25,32)(H,26,31)(H,29,30)/t18-,19-,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Australian National University Curated by ChEMBL					Assay Description Competitive inhibition of secreted PAM in human DMS53 cell culture medium using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysis				Bioorg Med Chem Lett 22: 7015-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.004 BindingDB Entry DOI: 10.7270/Q2VT1T73
					More data for this Ligand-Target Pair