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Found 1 hit Enz. Inhib. hit(s) with Target = 'Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1' and Ligand = 'BDBM50437702'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1


(Homo sapiens (Human))		BDBM50437702
PNG
(CHEMBL2409069)
Show SMILES [#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8]P([#8])([#8])=O)\[#6]=[#6]-1\[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](-[#7])=O |r|
Show InChI InChI=1S/C35H49N8O9P/c1-22(44)40-29(18-23-10-4-2-5-11-23)34(48)43-30(19-24-12-6-3-7-13-24)33(47)41-26(21-52-53(49,50)51)20-25-14-8-15-27(25)32(46)42-28(31(36)45)16-9-17-39-35(37)38/h2-7,10-13,20,26-30H,8-9,14-19,21H2,1H3,(H2,36,45)(H,40,44)(H,41,47)(H,42,46)(H,43,48)(H4,37,38,39)(H2,49,50,51)/b25-20-/t26-,27-,28+,29+,30+/m1/s1
PDB
MMDB

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PC cid
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UniChem
Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Horizon Discovery

Curated by ChEMBL


Assay Description
Inhibition of Pin1 (unknown origin) using Suc-Ala-Glu-cis-Pro-Phe-pNA as substrate

Bioorg Med Chem Lett 23: 4283-91 (2013)


Article DOI: 10.1016/j.bmcl.2013.05.088
BindingDB Entry DOI: 10.7270/Q2DV1M9T
More data for this
Ligand-Target Pair