Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Period circadian protein homolog 2' and Ligand = 'BDBM50140692'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140692 (CHEMBL3754517 | US10383880, Example 84) Show SMILES OC(CN(Cc1ccco1)S(=O)(=O)C1CCCCC1)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C26H30N2O4S/c29-20(18-28-25-14-6-4-12-23(25)24-13-5-7-15-26(24)28)17-27(19-21-9-8-16-32-21)33(30,31)22-10-2-1-3-11-22/h4-9,12-16,20,22,29H,1-3,10-11,17-19H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	892	n/a	n/a	n/a	n/a
Synchronicity US Patent					Assay Description Per2 Assay for Evaluating the Potency of Test Compounds.				US Patent US10383880 (2019) BindingDB Entry DOI: 10.7270/Q2J67K8X
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140692 (CHEMBL3754517 | US10383880, Example 84) Show SMILES OC(CN(Cc1ccco1)S(=O)(=O)C1CCCCC1)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C26H30N2O4S/c29-20(18-28-25-14-6-4-12-23(25)24-13-5-7-15-26(24)28)17-27(19-21-9-8-16-32-21)33(30,31)22-10-2-1-3-11-22/h4-9,12-16,20,22,29H,1-3,10-11,17-19H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair