Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Period circadian protein homolog 2' and Ligand = 'BDBM50140915'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140915 (CHEMBL3754372 | US10383880, Example 45) Show SMILES CCN(CC(O)Cn1c2ccccc2c2ccccc12)S(C)(=O)=O Show InChI InChI=1S/C18H22N2O3S/c1-3-19(24(2,22)23)12-14(21)13-20-17-10-6-4-8-15(17)16-9-5-7-11-18(16)20/h4-11,14,21H,3,12-13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	505	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140915 (CHEMBL3754372 | US10383880, Example 45) Show SMILES CCN(CC(O)Cn1c2ccccc2c2ccccc12)S(C)(=O)=O Show InChI InChI=1S/C18H22N2O3S/c1-3-19(24(2,22)23)12-14(21)13-20-17-10-6-4-8-15(17)16-9-5-7-11-18(16)20/h4-11,14,21H,3,12-13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	398	n/a	n/a	n/a	n/a
Synchronicity US Patent					Assay Description Per2 Assay for Evaluating the Potency of Test Compounds.				US Patent US10383880 (2019) BindingDB Entry DOI: 10.7270/Q2J67K8X
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140915 (CHEMBL3754372 | US10383880, Example 45) Show SMILES CCN(CC(O)Cn1c2ccccc2c2ccccc12)S(C)(=O)=O Show InChI InChI=1S/C18H22N2O3S/c1-3-19(24(2,22)23)12-14(21)13-20-17-10-6-4-8-15(17)16-9-5-7-11-18(16)20/h4-11,14,21H,3,12-13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	390	n/a	n/a	n/a	n/a
Synchronicity US Patent					Assay Description Per2 Assay for Evaluating the Potency of Test Compounds.				US Patent US10383880 (2019) BindingDB Entry DOI: 10.7270/Q2J67K8X
					More data for this Ligand-Target Pair