BindingDB PrimarySearch

Found 30 hits Enz. Inhib. hit(s) with Target = 'Peroxisome proliferator-activated receptor alpha' and Ligand = 'BDBM28700'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards peroxisome proliferator activated receptor alpha (PPAR alpha)				Bioorg Med Chem Lett 13: 3185-90 (2003) BindingDB Entry DOI: 10.7270/Q2TQ6229
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Peroxisome proliferator activated receptor alpha				J Med Chem 48: 2248-50 (2005) Article DOI: 10.1021/jm0496436 BindingDB Entry DOI: 10.7270/Q2SX6CRR
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Co Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from hPPARalpha				Bioorg Med Chem Lett 16: 6328-33 (2006) Article DOI: 10.1016/j.bmcl.2006.09.011 BindingDB Entry DOI: 10.7270/Q2PK0FSC
Eli Lilly and Co Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of tritium labeled ligand from human PPARalpha by SPA assay				Bioorg Med Chem Lett 16: 6293-7 (2006) Article DOI: 10.1016/j.bmcl.2006.09.028 BindingDB Entry DOI: 10.7270/Q23R0TNK
Lilly Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Mean inhibitory concentration against human peroxisome proliferator activated receptor alpha				Bioorg Med Chem Lett 15: 51-5 (2004) Article DOI: 10.1016/j.bmcl.2004.10.042 BindingDB Entry DOI: 10.7270/Q24B30T6
Lilly Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Eli Lilly & Company Curated by ChEMBL					Assay Description Inhibitory activity against human Peroxisome proliferator activated receptor alpha				J Med Chem 46: 5121-4 (2003) Article DOI: 10.1021/jm034173l BindingDB Entry DOI: 10.7270/Q2D50MB0
Division of Eli Lilly & Company Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human Peroxisome proliferator activated receptor alpha binding				J Med Chem 48: 2262-5 (2005) Article DOI: 10.1021/jm048993p BindingDB Entry DOI: 10.7270/Q2VT1RM6
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	6.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human peroxidase proliferator activated receptor alpha (hPPARalpha)				J Med Chem 44: 2061-4 (2001) BindingDB Entry DOI: 10.7270/Q2DZ07KH
Lilly Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.06E+5	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 2(S)-(2-benzoyl-phenylamino)-3-{4-[1,1-ditritio-2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-propionic acid from G...				Bioorg Med Chem Lett 19: 2468-73 (2009) Article DOI: 10.1016/j.bmcl.2009.03.036 BindingDB Entry DOI: 10.7270/Q2QC03C3
F. Hoffmann-La Roche Ltd Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	2.65E+3	n/a	n/a	n/a	n/a
Eli Lilly and Co Curated by ChEMBL					Assay Description Activity at human PPARalpha in CV1 cells				Bioorg Med Chem Lett 16: 6328-33 (2006) Article DOI: 10.1016/j.bmcl.2006.09.011 BindingDB Entry DOI: 10.7270/Q2PK0FSC
Eli Lilly and Co Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Activity at human liver PPAR alpha expressed in HEK293 cells by PPAR-GAL4 transactivation assay				J Med Chem 50: 1495-503 (2007) Article DOI: 10.1021/jm061202u BindingDB Entry DOI: 10.7270/Q2J9662B
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	6.90E+4	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha by luciferase reporter transactivation assay				Bioorg Med Chem Lett 19: 2468-73 (2009) Article DOI: 10.1016/j.bmcl.2009.03.036 BindingDB Entry DOI: 10.7270/Q2QC03C3
F. Hoffmann-La Roche Ltd Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Curated by ChEMBL					Assay Description Agonist activity at GAL4-tagged human PPARalpha ligand binding domain expressed in human HepG2 cells assessed as receptor transactivation by lucifera...				J Med Chem 52: 6382-93 (2009) Article DOI: 10.1021/jm900941b BindingDB Entry DOI: 10.7270/Q2862GHF
Universit£ degli Studi di Bari Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co, Ltd Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha ligand binding domain expressed in COS-1 cells cotransfected with Gal4 by luciferase reporter gene assay				Bioorg Med Chem Lett 21: 220-4 (2010) Article DOI: 10.1016/j.bmcl.2010.11.032 BindingDB Entry DOI: 10.7270/Q2668DGT
Dainippon Sumitomo Pharma Co, Ltd Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co, Ltd Curated by ChEMBL					Assay Description Partial agonist activity at human PPARalpha expressed in CHO cells cotransfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by tra...				Bioorg Med Chem Lett 21: 1978-82 (2011) Article DOI: 10.1016/j.bmcl.2011.02.032 BindingDB Entry DOI: 10.7270/Q2PC32N3
Dainippon Sumitomo Pharma Co, Ltd Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a
Korea University Curated by ChEMBL					Assay Description Binding affinity to histidine-tagged human PPARalpha-LBD assessed as recruitment of co-activator peptide fluorescein-labeled PGC1alpha after 2 hrs by...				Bioorg Med Chem Lett 21: 5876-80 (2011) Article DOI: 10.1016/j.bmcl.2011.07.095 BindingDB Entry DOI: 10.7270/Q2TD9XRN
Korea University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at human recombinant PPARalpha by transactivation of TK-MH100x4-LUC reporter gene in HEK293 cells				Bioorg Med Chem Lett 16: 3213-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.075 BindingDB Entry DOI: 10.7270/Q2KD1ZPZ
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
Nippon Shinyaku Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha expressed in monkey CV1 cells by transactivation assay				Bioorg Med Chem Lett 18: 2128-32 (2008) Article DOI: 10.1016/j.bmcl.2008.01.086 BindingDB Entry DOI: 10.7270/Q2K0755V
Nippon Shinyaku Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of tritium labeled ligand from human PPARalpha by SPA assay				Bioorg Med Chem Lett 16: 6293-7 (2006) Article DOI: 10.1016/j.bmcl.2006.09.028 BindingDB Entry DOI: 10.7270/Q23R0TNK
Lilly Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Nippon Shinyaku Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha expressed in CV1 cells by transactivation assay				Bioorg Med Chem 16: 981-94 (2008) Article DOI: 10.1016/j.bmc.2007.10.007 BindingDB Entry DOI: 10.7270/Q2862H95
Nippon Shinyaku Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Effective concentration against human Peroxisome proliferator activated receptor alpha				J Med Chem 48: 2248-50 (2005) Article DOI: 10.1021/jm0496436 BindingDB Entry DOI: 10.7270/Q2SX6CRR
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration against human Peroxisome proliferator activated receptor alpha in Gal4 transactivation assay				J Med Chem 48: 2262-5 (2005) Article DOI: 10.1021/jm048993p BindingDB Entry DOI: 10.7270/Q2VT1RM6
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Mean effective concentration against human peroxisome proliferator activated receptor alpha				Bioorg Med Chem Lett 15: 51-5 (2004) Article DOI: 10.1016/j.bmcl.2004.10.042 BindingDB Entry DOI: 10.7270/Q24B30T6
Lilly Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Rattus norvegicus)	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.31E+5	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro transactivation of rat Peroxisome proliferator activated receptor alpha				J Med Chem 46: 4883-94 (2003) Article DOI: 10.1021/jm0309046 BindingDB Entry DOI: 10.7270/Q2222T5V
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	3.21E+4	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro transactivation of human Peroxisome proliferator activated receptor alpha (hPPARalpha)				J Med Chem 46: 4883-94 (2003) Article DOI: 10.1021/jm0309046 BindingDB Entry DOI: 10.7270/Q2222T5V
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a
Division of Eli Lilly & Company Curated by ChEMBL					Assay Description Cotransfection activity of compound against human Peroxisome proliferator activated receptor alpha was determined				J Med Chem 46: 5121-4 (2003) Article DOI: 10.1021/jm034173l BindingDB Entry DOI: 10.7270/Q2D50MB0
Division of Eli Lilly & Company Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
Glaxo Wellcome Research & Development Curated by ChEMBL					Assay Description Compound was tested for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected CV-1 cells				J Med Chem 42: 3785-8 (1999) BindingDB Entry DOI: 10.7270/Q29C6WM9
Glaxo Wellcome Research & Development Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
Terns Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PPARalpha (unknown origin)				J Med Chem 63: 5031-5073 (2020) Article DOI: 10.1021/acs.jmedchem.9b01701 BindingDB Entry DOI: 10.7270/Q2DJ5JXG
Terns Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
GSK					Assay Description The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...				J Med Chem 50: 685-95 (2007) Article DOI: 10.1021/jm058056x BindingDB Entry DOI: 10.7270/Q2RN3669
GSK					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Mus musculus)	BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a
Glaxo Wellcome Research & Development Curated by ChEMBL					Assay Description Compound was tested for its agonist activity against murine Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor transfected CV-1 ...				J Med Chem 42: 3785-8 (1999) BindingDB Entry DOI: 10.7270/Q29C6WM9
Glaxo Wellcome Research & Development Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)