Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM28799 (2-{[4-(2-{[(2,4-difluorophenyl)carbamoyl](heptyl)a...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research & Development Curated by ChEMBL | Assay Description Compound was tested for agonist activity on human Peroxisome proliferator activated receptor delta-GAL4 chimeric receptor in transfected CV-1 cells | J Med Chem 42: 3785-8 (1999) BindingDB Entry DOI: 10.7270/Q29C6WM9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor delta (Mus musculus) | BDBM28799 (2-{[4-(2-{[(2,4-difluorophenyl)carbamoyl](heptyl)a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research & Development Curated by ChEMBL | Assay Description Compound was tested for its agonist activity against murine Peroxisome proliferator activated receptor delta-GAL4 chimeric receptor in transfected CV... | J Med Chem 42: 3785-8 (1999) BindingDB Entry DOI: 10.7270/Q29C6WM9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM28799 (2-{[4-(2-{[(2,4-difluorophenyl)carbamoyl](heptyl)a...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research & Development Curated by ChEMBL | Assay Description Agonist activity for Human PPAR delta receptor in transcriptional activation assay | J Med Chem 43: 527-50 (2000) BindingDB Entry DOI: 10.7270/Q2H994DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor delta (Mus musculus) | BDBM28799 (2-{[4-(2-{[(2,4-difluorophenyl)carbamoyl](heptyl)a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research & Development Curated by ChEMBL | Assay Description Agonist activity for murine PPAR delta receptor in transcriptional activation assay | J Med Chem 43: 527-50 (2000) BindingDB Entry DOI: 10.7270/Q2H994DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM28799 (2-{[4-(2-{[(2,4-difluorophenyl)carbamoyl](heptyl)a...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 150 | n/a | n/a | n/a | n/a |
Johnson& Johnson Curated by ChEMBL | Assay Description Agonist activity at PPARdelta expressed in HEK293 cells by GAL4 transactivation assay | Bioorg Med Chem Lett 17: 6773-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.041 BindingDB Entry DOI: 10.7270/Q27945H6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM28799 (2-{[4-(2-{[(2,4-difluorophenyl)carbamoyl](heptyl)a...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
Universidade de Vigo Curated by ChEMBL | Assay Description Agonist activity at PPARdelta ligand binding domain expressed in human HeLa cells cotransfected with Gal4-DBD assessed as transcriptional activation ... | Bioorg Med Chem Lett 19: 1883-6 (2009) Article DOI: 10.1016/j.bmcl.2009.02.072 BindingDB Entry DOI: 10.7270/Q2K35THG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor delta (Mus musculus) | BDBM28799 (2-{[4-(2-{[(2,4-difluorophenyl)carbamoyl](heptyl)a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a |
Bayer-Schering Pharma Curated by ChEMBL | Assay Description Agonist activity at Gal4-fused mouse PPARdelta | Bioorg Med Chem Lett 20: 3376-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.019 BindingDB Entry DOI: 10.7270/Q27944V8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM28799 (2-{[4-(2-{[(2,4-difluorophenyl)carbamoyl](heptyl)a...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a |
Bayer-Schering Pharma Curated by ChEMBL | Assay Description Agonist activity at Gal4-fused human PPARdelta | Bioorg Med Chem Lett 20: 3376-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.019 BindingDB Entry DOI: 10.7270/Q27944V8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM28799 (2-{[4-(2-{[(2,4-difluorophenyl)carbamoyl](heptyl)a...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description In vitro transcriptional activation in CV-1 cells expressing human Gal4-PPAR delta ligand binding domain | Bioorg Med Chem Lett 11: 1225-7 (2001) BindingDB Entry DOI: 10.7270/Q2Z31XX0 | |||||||||||
More data for this Ligand-Target Pair |