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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Peroxisome proliferator-activated receptor delta' and Ligand = 'BDBM50312377'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM50312377
PNG
(2-(4-((4,5-bis(4-(trifluoromethyl)phenyl)thiazol-2...)
Show SMILES Cc1cc(OCc2nc(c(s2)-c2ccc(cc2)C(F)(F)F)-c2ccc(cc2)C(F)(F)F)ccc1OCC(O)=O
Show InChI InChI=1S/C27H19F6NO4S/c1-15-12-20(10-11-21(15)38-14-23(35)36)37-13-22-34-24(16-2-6-18(7-3-16)26(28,29)30)25(39-22)17-4-8-19(9-5-17)27(31,32)33/h2-12H,13-14H2,1H3,(H,35,36)
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Article
PubMed
n/an/an/an/a 350n/an/an/an/a



The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...


J Med Chem 53: 77-105 (2010)


Article DOI: 10.1021/jm9007399
BindingDB Entry DOI: 10.7270/Q28052RP
More data for this
Ligand-Target Pair