Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3-kinase regulatory subunit alpha' and Ligand = 'BDBM340312'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human))	BDBM340312 ((Scheme A): Preparation of [(3S)-3-{[2′-amin...) Show SMILES Nc1ncc(cn1)-c1nc(nc(N[C@@]2(CO)CCN(C2)C(=O)C2(F)CC2)c1F)N1CCOCC1 |r| Show InChI InChI=1S/C21H26F2N8O3/c22-14-15(13-9-25-18(24)26-10-13)27-19(30-5-7-34-8-6-30)28-16(14)29-20(12-32)3-4-31(11-20)17(33)21(23)1-2-21/h9-10,32H,1-8,11-12H2,(H2,24,25,26)(H,27,28,29)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PFIZER INC. US Patent					Assay Description The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...				US Patent US9758538 (2017) BindingDB Entry DOI: 10.7270/Q27D2X70
					More data for this Ligand-Target Pair