Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM122465'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM122465 (US8729074, 4) Show SMILES Cc1ccn2c(cnc2c1)-c1cnc(Cl)c(NS(=O)(=O)c2ccc(F)cc2)c1 Show InChI InChI=1S/C19H14ClFN4O2S/c1-12-6-7-25-17(11-22-18(25)8-12)13-9-16(19(20)23-10-13)24-28(26,27)15-4-2-14(21)3-5-15/h2-11,24H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	19	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The PI3K AlphaScreen assay (PerkinElmer, Waltham, Mass.) measures the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI3Kβ,...				US Patent US8729074 (2014) BindingDB Entry DOI: 10.7270/Q2RJ4H4G
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