Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM122469'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM122469 (US8729074, 23) Show SMILES CN(C)S(=O)(=O)Nc1cc(cnc1Cl)-c1cnc2cc(C)c(cn12)-c1ccncc1 Show InChI InChI=1S/C20H19ClN6O2S/c1-13-8-19-23-11-18(27(19)12-16(13)14-4-6-22-7-5-14)15-9-17(20(21)24-10-15)25-30(28,29)26(2)3/h4-12,25H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The PI3K AlphaScreen assay (PerkinElmer, Waltham, Mass.) measures the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI3Kβ,...				US Patent US8729074 (2014) BindingDB Entry DOI: 10.7270/Q2RJ4H4G
					More data for this Ligand-Target Pair