Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM125457'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM125457 (US8772480, 312) Show SMILES COc1ncc(Nc2ncc(cc2-c2nc(C)nc(N)n2)C(C)CO)cc1F Show InChI InChI=1S/C18H20FN7O2/c1-9(8-27)11-4-13(16-23-10(2)24-18(20)26-16)15(21-6-11)25-12-5-14(19)17(28-3)22-7-12/h4-7,9,27H,8H2,1-3H3,(H,21,25)(H2,20,23,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The PI3K AlphaScreen assay (PerkinElmer, Waltham, Mass.) measures the activity of a panel of four phosphoinositide 3-kinases: PI3Kalpha, PI3Kbeta, PI...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM125457 (US8772480, 312) Show SMILES COc1ncc(Nc2ncc(cc2-c2nc(C)nc(N)n2)C(C)CO)cc1F Show InChI InChI=1S/C18H20FN7O2/c1-9(8-27)11-4-13(16-23-10(2)24-18(20)26-16)15(21-6-11)25-12-5-14(19)17(28-3)22-7-12/h4-7,9,27H,8H2,1-3H3,(H,21,25)(H2,20,23,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The PI3K AlphaScreen assay (PerkinElmer, Waltham, Mass.) measures the activity of a panel of four phosphoinositide 3-kinases: PI3Kalpha, PI3Kbeta, PI...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM125457 (US8772480, 312) Show SMILES COc1ncc(Nc2ncc(cc2-c2nc(C)nc(N)n2)C(C)CO)cc1F Show InChI InChI=1S/C18H20FN7O2/c1-9(8-27)11-4-13(16-23-10(2)24-18(20)26-16)15(21-6-11)25-12-5-14(19)17(28-3)22-7-12/h4-7,9,27H,8H2,1-3H3,(H,21,25)(H2,20,23,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The PI3K AlphaScreen assay (PerkinElmer, Waltham, Mass.) measures the activity of a panel of four phosphoinositide 3-kinases: PI3Kalpha, PI3Kbeta, PI...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair