Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM125517'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM125517 (US8772480, 146) Show SMILES COc1ccc(Nc2ncc(cc2-c2nc(C)nc(N)n2)[C@@H](C)N2CCN(CC2)S(C)(=O)=O)cn1 |r| Show InChI InChI=1S/C22H29N9O3S/c1-14(30-7-9-31(10-8-30)35(4,32)33)16-11-18(21-26-15(2)27-22(23)29-21)20(25-12-16)28-17-5-6-19(34-3)24-13-17/h5-6,11-14H,7-10H2,1-4H3,(H,25,28)(H2,23,26,27,29)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The PI3K AlphaScreen assay (PerkinElmer, Waltham, Mass.) measures the activity of a panel of four phosphoinositide 3-kinases: PI3Kalpha, PI3Kbeta, PI...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair