Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM291356'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM291356 (4-Morpholin-4-yl-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)...) Show SMILES C1CN(CCO1)c1nc(nc2c3cccnc3oc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C20H16N6O2/c1-2-14-15-16(28-20(14)23-5-1)19(26-8-10-27-11-9-26)25-18(24-15)13-4-7-22-17-12(13)3-6-21-17/h1-7H,8-11H2,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
Lek Pharmaceuticals d.d.					Assay Description Please see article				J Med Chem 51: 7486-94 (2008) BindingDB Entry DOI: 10.7270/Q21V5H9P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM291356 (4-Morpholin-4-yl-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)...) Show SMILES C1CN(CCO1)c1nc(nc2c3cccnc3oc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C20H16N6O2/c1-2-14-15-16(28-20(14)23-5-1)19(26-8-10-27-11-9-26)25-18(24-15)13-4-7-22-17-12(13)3-6-21-17/h1-7H,8-11H2,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
Karus Therapeutics Limited US Patent					Assay Description PI3K Isoform using biochemical assay.				US Patent US9580442 (2017) BindingDB Entry DOI: 10.7270/Q2J38VM2
					More data for this Ligand-Target Pair