Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50089301'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50089301 (CHEMBL3577923) Show SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(Cl)s1)-c1cc2c(ncnc2s1)-c1ccncc1 Show InChI InChI=1S/C21H14ClN5O3S3/c1-30-20-15(27-33(28,29)18-3-2-17(22)32-18)8-13(10-24-20)16-9-14-19(12-4-6-23-7-5-12)25-11-26-21(14)31-16/h2-11,27H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
PKUCare Pharmaceutical R&D Center Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) using PIP2/PS as substrate after 1 hr by luciferase-based luminescence assay				ACS Med Chem Lett 6: 434-8 (2015) Article DOI: 10.1021/ml5005014 BindingDB Entry DOI: 10.7270/Q29Z96M1
					More data for this Ligand-Target Pair